Born in a time where his people dwelled in Amol-Kalit, HotepseAken was once named Imset-Setmat. A passionate and studios learner, he took up the dual swords of the Fanatics and swore to ensure the sanctity of the Tomb City. For uncounted years, he ranged across Amol-Kalit, slaying trespassers and devouring their souls. Raids for fresh speciments were often his job, and he relished bringing his people closer to their divine goal: To find and cure all ills. It was only when the Gnolls along the north coast chose to serve did his xenophobic extremism cease, failing to understand for a time that other creatures could see the value of their work. After many years of introspection, he chose a new name: Hotepse.

As Hotepse, he renounced his fanatical frenzy to advance his people's goals, choosing instead to apply their knowledge. First upon the Gnolls, he helped reduce their miscarriage rates to near-zero, and infant mortality to similar levels. This proximity to other races began to reveal more of the world to the Anaphite than he had ever considered. Before, other creatures were lesser races, animals. Now, he could see they felt, they loved, and they had dreams. No more could Hotepse bring them ruin for some vague goal of an end to suffering. The cure to all that brought pain could not, itself, cause suffering, lest the panacea be tainted. Now, Hotepse travels, given the named HotepseAken or "Helpful to men's peace" as they research the races of the world through curing their diseases, removing their sickness, and aiding those in need.